Environment-responsive polymers for coating of pharmaceutical nanocarriers

Book Review: Smart Pharmaceutical Nanocarriers

Trigger responsive polymeric nanocarriers for cancer therapy.

Conventional chemotherapy for the treatment of cancer has limited specificity when administered systemically and is often associated with toxicity issues. Enhanced accumulation of polymeric nanocarriers at a tumor site may be achieved by passive and active targeting. Incorporation of trigger responsiveness into these polymeric nanocarriers improves the anticancer efficacy of such systems by mod...

Roughness Model for Adhesion Testing of Pharmaceutical Coating Materials

Objective Roughness is the main parameter in interlocking bonding mechanism. Yet there is no model designed to evaluate the effect of surface roughness on adhesion of coating materials in pharmaceutical sciences. Materials and Methods In this study polymethyl metacrylate spherical beads with different sizes were poured into 10 mm mold, then it was pressed by hand screw and finally heated to 141...

Tatp-mediated intracellular delivery of pharmaceutical nanocarriers.

CPPs (cell-penetrating peptides), including Tatp (transactivator of transcription peptide), have been successfully used for intracellular delivery of a wide variety of cargoes including various nanoparticulate pharmaceutical carriers such as liposomes, micelles and nanoparticles. Here, we will consider the major results obtained in this area with emphasis on Tatp-mediated delivery of liposomes ...

Plasma Technology for Removal of Pharmaceutical Compounds from the Environment